Fengzhu Sun (Publications since 1995)

 

95.

Zhai ZY, Reinert G, Song K, Waterman MS, Luan YH, Sun FZ (2012) Normal and Compound Poisson Approximations for Pattern Occurrences in NGS Reads. In Press, Journal of Computational Biology

94.

Song K, Ren J, Zhai ZY, Liu XM, Deng MH, Sun FZ (2012) Alignment-free sequence comparison based on NGS reads: extended abstract. Accepted, RECOMB2012 Proceedings

93.

Chang Q, Luan YH, Chen T, Fuhrman JA, Sun FZ (2012) Computational methods for the analysis of tag sequences in metagenomics studies. In press, Frontiers in Bioscience, S4, 1333-1343, June 1.

92.

Wan L, Yan XT, Chen T, Sun FZ (2012) Modeling RNA degradation for RNA-Seq with applications(Program). Biostatistics, published online Feb. 21, 2012

91.

Wan L, Sun FZ (2012) CEDER: Accurate detection of differentially expressed genes by combining significance of exons using RNA-Seq. To appear, IEEE/ACM Transactions on Computational Biology and Bioinformatics (APBC2012), 9(1), JANUARY/FEBRUARY 2012

90.

Xia L, Cram JA, Chen T, Fuhrman JA, Sun FZ (2011) Accurate genome relative abundance estimation based on shotgun metagenomic reads (Program). PLoS One 6(12): e27992

89.

Xia L, Steele JA, Cram JA, Cardon ZG, Simmons SL, Vallino JL, Fuhrman JA, Sun FZ (2011) Extended local similarity analysis (eLSA) of microbial community and other time series data with replicates (Program). BMC Systems Biology (GIW2012)5(Suppl 2):S15

88.

Liu XM, Wan L, Li J, Reinert R, Waterman MS, Sun FZ (2011) New powerful statistics for alignment-free sequence comparison under a pattern transfer model. Journal of Theoretical Biology 284(1):106-116

87.

Chang Q, Luan YH, Sun FZ (2011) Variance adjusted weighted UniFrac: a powerful beta diversity measure for comparing communities based on phylogeny. BMC Bioinformatics 12:118

86.

Zhang WS, Sun FZ, Jiang R (2011) DomainRBF: a Bayesian regression approach to the prioritization of associations between protein domains and human complex diseases. BMC Systems Biology 5:55.

85.

He F, Zhou JY, Hu YQ, Sun FZ, Yang JY, Lin SL, Fung WK (2011) Detection of parent-of-origin effects for quantitative traits in complete and incomplete nuclear families with multiple children. Am J Epidemiology 174 (2): 226-233.

84.

Steele JA, Countway PD, Xia L, Vigil PD, Beman JM, Kim DY, Chow CET, Sachdeva R, Jones AC, Schwalbach MS, Rose JM, Hewson I, Patel A, Sun FZ, Caron DA, Fuhrman JA (2011) Marine bacterial, archaeal, and protistan association networks reveal ecological linkages. The ISME Journal 5:1414-1425.

83.

Meng L, Sun FZ, Zhang XG, Waterman MS (2011) Sequence alignment as hypothesis testing. Journal of Computational Biology 18(5):677-691.

82.

Zhang WS, Sun FZ, Jiang R (2011) Integrating multiple protein-protein interaction networks to prioritize disease genes: A Bayesian regression approach. BMC Bioinformatics (APBC2011) 12(Suppl 1):S11.

81.

Yu H, Pei GJ, Ge P, Fang XZ, Sun FZ, Lai LH, Qian MP, Deng MH (2010) Predicting kinase functional sites using hierarchical stochastic language modeling. Statistics and its Interface 3:523-532.

80.

Zhai ZY, Ku SY, Luan YH, Reinert G, Waterman MS, Sun FZ (2010) The Power of Detecting Enriched Patterns: An HMM Approach. Journal of Computational Biology 17(4):581-592. PMID: 20426691(software)

79.

Wan L, Reinert G, Sun FZ, Waterman MS (2010) Alignment free sequence comparison (II): theoretical power of comparison statistics. Journal of Computational Biology 17(11): 1349-1372. PMID: 20973742 (software)

78.

Reinert G, Chew D, Sun FZ, Waterman MS (2009) Alignment free sequence comparison (I): statistics and power. Journal of Computational Biology 16(12): 1615-1634 (software)

77.

Zhou LQ, Ma XT, Arbeitman MN, Sun FZ (2009) Chromatin regulation and gene centrality are essential for controlling fitness pleiotropy in Yeast. PLoS ONE 4(11): e8086

76.

Sanders LE, Lebo MS, Dalton JE, Sun FZ, Arbeitman MN (2009) Ecdysone receptor mediates courtship behaviors in Drosophila by acting in the fruitless circuit in an isoform-specific manner. Current Biology 19:1447-1452

75.

Wang L, Tu Z, Sun FZ (2009) A network-based integrative approach to prioritize reliable hits from multiple genome-wide RNAi screens in Drosophila (ISMB 2010 highlight track). BMC Genomics 10:220 (software)

74.

Jiang R, Chen T, Sun FZ (2009) Bayesian models and Gibbs sampling strategies for local graph alignment and network motif identification in stochastic biological networks. Communications in Systems and Information 9(4):347-370

73.

Lebo MS, Sanders LE , Sun FZ, Arbeitman MN(2009) Somatic, Germline and Sex Hierarchy Regulated Gene Expression During Drosophila Metamorphosis. BMC Genomics 10:80

72.

Wang WH, Nunez-Iglesias J, Luan YH, Sun FZ (2009) Usefulness and limitations of dK random graph models to predict interactions and functional homogeneity in biological networks under a pseudo-likelihood parameter estimation approach. BMC Bioinformatics 10:277

71.

Wang L, Sun FZ, Chen T (2008) Prioritizing functional modules mediating genetic perturbations and their phenotypic effects: a global strategy (ISMB 2009 highlight track). Genome Biology 9:R174

70.

Wan L, Li DY, Zhang DL, Liu X, Fu WJ, Zhu LH, Deng MH, Sun FZ, Qian MP (2008) Conservation and implications of eukaryote transcriptional regulatory regions across multiple species. BMC Genomics 9:623

69.

Yan XT, Sun FZ (2008) Testing gene set enrichment for subset of genes:Sub-GSE. BMC Bioinformatics 9:362 (software)

68.

Peña-Castillo et al. (2008) A critical assessment of Mus musculus gene function prediction using integrated genomic evidence. Genome Biology 9(Suppl 1):S2

67.

Pape UJ, Rahmann S, Sun FZ, Vingron M (2008) Compound poisson approximation of the number of occurrences of a Position Frequency Matrix (PFM) on both strands. Journal of Computational Biology 15(6): 547-564.

66.

Zhou LQ, Ma XT, Sun FZ (2008) The effects of protein interactions, gene essentiality and regulatory regions on expression variation. BMC Systems Biology 2:54

65.

Cheng C, Yan X, Sun F, Li LM (2007) Inferring activity changes of transcription factors by binding association with sorted expression profiles. BMC Bioinformatics 8:452.

64.

Jiang R, Yang H, Zhou LQ, Kuo CCJ, Sun FZ, Chen T (2007) Sequence-based prioritization of nonsynonymous single nucleotide polymorphisms for the study of disease mutations. Am J Hum Genet 81:346-360

63.

Yang Q, Kim SK, et al. (2007) Evidence of mitochondrial DNA involvement in hypertension and systolic blood pressure: the Framingham heart study. Journal of Hypertension 25(10):2067-2073

62.

Ma XT, Lee HJ, Wang L, Sun FZ (2007) CGI: A new approach for prioritizing genes by Combining Gene expression and protein-protein Interaction data. Bioinformatics 23:215-221 (software)

61.

Hu YQ, Zhou JY, Sun FZ, Fung WK (2007) The transmission disequilibrium test and imprinting effects test based on case-parent pairs. Genetic Epidemiology 31:273-287

60.

Rui Jiang, Zhidong Tu, Ting Chen, Fengzhu Sun (2006) Network motif identification in stochastic networks (ISMB 2007 highlight track) (Program). Proc Natl Acad Sci USA 103:9404-9409

59.

Jiang R, Yang H, Sun FZ, Chen T (2006) Searching for interpretable rules for disease mutations: A simulated annealing bump hunting strategy. BMC Bioinformatics 7:417

58.

Cheng C, Ma XT, Yan XT, Sun FZ, Li LM (2006) MART: a new method to detect differential gene expression in treatment-control time courses. Bioinformatics 22:2650-2657

 

57.

Hyunju Lee, Minghua Deng, Fengzhu Sun, Ting Chen (2006) An integrated approach to the prediction of domain-domain interactions. BMC Bioinformatics 7:269

56.

Hyunju Lee, Zhidong Tu , Minghua Deng, Fengzhu Sun, Ting Chen (2006) Diffusion kernel based logistic regression models for protein function prediction (Program). OMICS: A Journal of Integrative Biology, 10:40-55

55.

Quansong Ruan, Debojyoti Dutta, Michael S. Schwalbach, Joshua A. Steele, Jed A. Fuhrman, and Fengzhu Sun (2006) Local similarity analysis reveals unique associations among marine bacterioplankton species and environmental factors (program). Bioinformatics 22:2532-2538

54.

Quansong Ruan, Joshua A. Steele, Michael S. Schwalbach, Jed A. Fuhrman, and Fengzhu Sun (2006)  A dynamic programming algorithm for binning microbial community profiles (program)Bioinformatics 22:1508-1514

53.

Nicolas P, Sun FZ, Li LM (2006) A model-based approach to selection of tag SNPs. BMC Bioinformatics 7:303


52.

Zhidong Tu, Li Wang, Michelle Arbeitman, Ting Chen & Fengzhu Sun (2006) An integrative approach for causal gene identification and gene regulatory pathway inference (Program). Bioinformatics (ISMB 2006) 22:e489-e496

 

51.

Zhidong Tu, Li Wang, Min Xu, Xianghong Zhou, Ting Chen & Fengzhu Sun (2006) Further understanding human disease genes by comparing with housekeeping genes and other genes. BMC Genomics 7:31

 

50.

Kui Zhang, Fengzhu Sun (2005) Assessing the power of tag SNPs in the mapping of quantitative trait loci (QTL) with extremal and random samples. BMC Genetics 6:51

 

49.

Kui Zhang, Zhaohui Qin, Ting Chen, Jun S. Liu, Michael S. Waterman, Fengzhu Sun (2005) HapBlock: Haplotype block partitioning and Tag SNP selection software using a set of dynamic programming algorithms (Program). Bioinformatics 21:131-134

 

48.

Kui Zhang, Fengzhu Sun, Hongyu Zhao (2005)   HAPLORE: A program for haplotype reconstruction in general pedigrees without recombination.  Bioinformatics 21:90-103

47.

Faina Schwartz, Arvi Duka, Fengzhu Sun, Jing Cui, Athanasios Manolis and Haralambos Gavras (2004)  Mitochondrial genome mutations in hypertensive individuals.   Hypertension17:629-635

 

46.

Schulze TG, Zhang K, Chen YS, Akula N, Sun FZ, McMahon FJ (2004)  Defining haplotype blocks and tag SNPs in the human genome.  Human Molecular Genetics 13 335-342

 

45.

Zhang K, Qin ZHS, Liu JS, Chen T, Waterman MS, Sun FZ (2004) Haplotype  block partitioning and tag SNP Selection using genotype data and their applications to association studies. Genome Research 14:908-916

44.

Deng MH, Tu ZD, Sun FZ, Chen T (2004) Mapping gene ontology to proteins based on protein–protein interaction data. Bioinformatics 20:895-902

43.

Deng MH, Chen T, Sun FZ (2004) Integrated probabilistic model for functional prediction of proteins, RECOMB2003. Also on Journal of Computational Biology, 11:463-476

42.

Li WT, Sun FZ, Grosse I (2004) Extreme-value distribution based gene selection criteria for discriminant microarray data analysis using logistic regression. RECOMB2003. Also on Journal of Computational Biology 11:215-226

41.

Lai YL, Sun FZ (2004) Sampling distribution for microsatellites amplified by PCR: mean field approximation and its application to genotyping. J Theor Biol, 228:185-194

40.

Kim SK, Zhang K, Sun FZ (2004) A comparison of different strategies for computing confidence intervals of the linkage disequilibrium measure D'.  Pacific Symposium on Biocomputing 2004:128-139

39.

Sung Kim, Kui Zhang, Fengzhu Sun (2003) Detecting susceptibility genes in case-control studies using set association analysis.  BMC Genetics 2003, 4(Suppl 1):S9

38.

Zhang K, Sun FZ, Waterman MS and Chen T (2003) Dynamic programming algorithms for  partitioning sequence variation in human chromosomes. HERMIS, 4:15-26. Also “Computer Mathematics and Its Applications; Advances and Developments (1994-2005)?E.A. Lipitakis, Editor, LEA Publishers (2006), 431-442

 

37.

Sun, FZ, Cui, J, Gavras, H, Schwartz, F (2003) A novel class of tests for the detection of mitochondrial DNAmutation involvement in diseases. Am J Hum Genet 72:1515-1526

 

36.

Zhang K, Sun FZ, Waterman MS,  Chen T (2003) Haplotype block partitioning with limited resources and applications to human chromosome 21 haplotype data. Am J Hum Genet 73 63-73

35.

Deng, MH, Sun FZ, Chen, T (2003) Assessment of the reliability of protein-protein interactions and protein function prediction (supplement).  Pacific Symposium on Biocomputing, PSB2003, 8:140-151

34.

Lai YL, Sun FZ (2003) The relationship between microsatellite slippage mutation rate and the number of repeat units. Mol Bio Evol 20: 2123-2131

33.

Lai YL, Sun FZ (2003) Microsatellite mutations during the polymerase chian reaction: mean field approximations and their applications. J Theor Biol, 224:127-137

32.

Lai YL, Shinde D, Sun FZ, Arnheim N (2003) The mutation process of microsatellites during the polymerase chain reaction. J Comp Biol, 10:143-155

31.

Shinde D, Lai YL, Sun FZ, Arnheim N (2003) Taq DNA polymerase slippage mutation rates measured by PCR and quasi-likelihood analysis: (CA/GT)n and (A/T)n microsatellites, Nucl Acids Res, 31 974-980

 

30.

Zhang K, Calabrese P, Nordborg M, and Sun FZ (2002) Haplotype block structure and its applications to association studies: power and study designs. Am J Hum Genet 71 1386-1394

 

29.

Zhang K, Deng MH, Chen T, Waterman MS, Sun FZ (2002) A dynamic programming algorithm for haplotype block partitioning (PROGRAM) Proc Natl Acad Sci USA 99 7335-7339

28.

Deng MH, Zhang K, Mehta S, Chen T, Sun FZ (2002) Prediction of protein function using protein-protein interaction data (supplement). The first IEEE Computer Society bioinformatics conference, CSB2002, 117-126. Also on Journal of Computational Biology, 10:947-960

27.

Deng MH, Mehta S, Sun FZ, Chen T (2002) Inferring domain-domain interactions from protein-protein interactions (supplement). RECOMB2002:117-126. Also on Genome Research 12:1540-1548.

 

26.

Zhang SL,  Zhang K, Li JM, Sun FZ, Zhao HY (2001) Test of linkage and association for quantitative traits in general pedigrees: the quantitative pedigree disequilibrium testGenet Epidemiol 21 S370-S375

 

25

Li JM, D Wang, JP Dong, RF Jiang, K Zhang, SL Zhang, HY Zhao, FZ Sun (2001) The power of transmission disequilibrium tests for quantitative traits. Genet Epidemiol 21 S632-S637

 

24.

Jiang R, Dong J, Wang D, Sun FZ (2001) Fine-scale mapping using Hardy-Weinberg Disequilibrium. Ann Hum Genet, 65 207-219

 

23.

Flanders WD, Sun FZ,  Yang QH (2001) A new estimator of the genotype risk ratio for use in case parental-control studies. Am J Epidemol 154 259-263

 

22.

Sun FZ,  Yang QH, Zhao HY, Flanders WD (2000) Transmission/disequilibrium tests for quantitative traits. Ann Hum Genet, 64 555-565

 

21.

Zhao HY, Zhang SL, Merikangas KR, Widenauer DB, Sun FZ, Kidd KK. (2000) Transmission/disequilibrium tests using multiple tightly linked markers. Am J Hum Genet, 67 936-946

 

20.

Yang QH, Khoury MJ, Coughlin SS, Sun FZ, Flanders WD (2000) On the use of population-based registries in the clinical validation of genetic testing for disease susceptibility. Genetics in Medicine, 2 186-192

19.

Wang D, Zhao C, Cheng R, Sun FZ (2000) Estimating the mutation rate during error-prone polymerase chain reaction. J Comp Biol, 7 143-158 

18.

Wang D, Sun FZ (2000) Sample sizes for the transmission/disequilibrium tests: The TDT, S-TDT and 1-TDT. Commun Stat-Theory M, 29 1129-1142 

17.

Sun FZ, Cheng R, Flanders WD, Yang QH, Khoury MJ (1999) Whole genome association studies for genes affecting alcohol dependence. Genet Epidemiol, 17 S337-342 

16.

Yang QH, Khoury MJ, Atkinson M, Sun FZ, Cheng R, Flanders WD (1999), Using case-control designs for genome wide screening for associations between genetic markers and disease susceptibility loci. Genet Epidemiol, 17 S779-784 

15.

Yang QH, Khoury MJ, Atkinson M, Sun FZ, Flanders WD (1999) Case-only design to measure gene-gene interactions. Epidemiology, 10 167-170 

14.

Sun FZ, Flanders WD, Yang QH, Khoury MJ (1999) Transmission disequilibrium test (TDT) when only one parent is available: The 1-TDT. Am J Epidemol, 150 97-104 

13.

Sun, FZ (1999) Modeling DNA shuffling. J Comp Biol, 6 77-90

12.

Sun FZ, Flanders WD, Yang QH, Khoury MJ (1998) A new method for estimating the risk ratio in studies using case-parental control design. Am J Epidemol, 148 902-909 

11.

Sun FZ, Ashley AE, Durham LK, Feingold E, Halloran ME, Manatunga AK, Sherman SL (1998) Testing for contributions of mitochondrial DNA mutations to complex diseases. Genet Epidemiol, 15 451-469 

10.

Bruno W, Sun FZ, Torney DC (1998) Optimum group testing designs for partially characterized objects. J Appl Math, 58 1043-1059

9.

Savage-Austin A, Sun FZ, Crawford DC, Ashley AE, Yang QH, Sherman SL (1997) Sequential sibpair and association studies to detect genes in quantitative traits. Genet Epidemiol, 14 885-890 

8.

Yang QH, Atkinson M, Sun FZ, Sherman SL, Khoury MJ (1997) The method of sib-pair linkage analysis in the context of case-control design. Genet Epidemiol, 14 939-944 

7.

Brown MD, Sun FZ, Wallace DC (1997) Clustering of Leber hereditary optic neuropathy patients on a Caucasian mitochondrial lineage. Am J Hum Genet, 60 381-387 

 

 

6.

Sun FZ, Benson G, Arnheim N, Waterman MS (1997) Pooling strategies for establishing physical genome maps using FISH. J Comp Biol, 4 467-486

5.

Sun FZ, Waterman MS (1997) Whole genome amplification and branching processes, Adv Appl Prob, 29 629-684

4.

Sun FZ, Galas D, Waterman MS (1996) A mathematical analysis of in vitro selection amplification. J Mol Biol, 258 650-660

3.

Sun FZ, Arnheim N, Waterman MS (1995) Whole genome amplification of single cells: mathematical analysis of PEP and tagged PCR. Nucleic Acids Research, 23 3034-3040. 

2.

Port E, Sun FZ, Martin D, Waterman MS (1995) Genomic mapping by end characterized random clones: A mathematical analysis. Genomics, 26 84-100 

1.

Sun FZ (1995) The polymerase chain reaction and branching processes. J Comp Biol, 23 3034-3040.

 

Book Chapters

9. Zhidong Tu, Jun Zhu, and Fengzhu Sun (2011) Inferring signaling and gene regulatory network from genetic and genomic information. Henry Horng-Shing Lu, Bernhard Scholkopf and Hongyu Zhao (editors): Handbook of Computational Statistics: Statistical Bioinformatics, Springer. Pp479-500.

 

8. Hyunju Lee, Ting Chen, Fengzhu Sun (2010) Domain-Domain Interactions. Jianfeng Feng, Wenjiang Fu,  Fengzhu Sun (Editors): Frontiers in Computational and Systems Biology. Springer.  Pp. 157-173.

 

7. Fengzhu Sun, Ting Chen, Minghua Deng, Hyunju Lee, Zhidong Tu (2010) Data integration for the study of protein interactions. In Darlene R . Goldstein and Rudy Guerra (Editors): Meta-analysis and Combining Information in Genetics and Genomics, Pp 259-274 Chapman and Hall

 

6. Kui Zhang, Fengzhu Sun (2007). Tag SNP Selection and Its Applications in Association Studies. Hongwen Deng, Hui Shen, Yongjun Liu, and Hai Hu (Editors): Current Topics in Human Genetics: Studies in Complex Diseases. World Scientific Publishing. pp. 95-122.

 

5. Xiucheng Feng, Lin Wan, Minghua Deng, Fengzhu Sun and Minping Qian (2007) An Efficient Algorithm for Deciphering Regulatory Motifs. Jianfeng Feng, Jürgen Jost and Minping Qian (Editors): Networks: From Biology to Theory, Part III.

 

4. Lai YL, Sun FZ (2004) Understanding the mutation mechanisms during polymerase chain reaction (extended abstract). In M. Huebner and M. Sorensen (eds) Workshop on Dynamical Stochastic Modeling in Biology, pages 59-68

 

3. Zhang K, Chen T, Waterman MS,  Sun FZ (2003) A set of dynamic algorithms for haplotype block partition and tag SNP selection via haplotype data and genotype data.  Computational Methods for SNPs and Haplotype Inference, Istrail S, Waterman M and Clark A (eds),  96-112

 

2. Sun FZ (2001) Stochastic modeling of polymerase chain reaction and related biotechnologies. Bulletin of the International Statistical Institute, 53rd session proceedings, book 1: 393-396.

 

1.   Sun FZ (1999) Biological and statistical studies for diseases involving mtDNA mutations. In: Halloran ME, Geisser S (eds) Statistics in Genetics. Springer, New York, pp 133-146.

 

Books

Frontiers in Computational and Systems Biology (2010) (in honor of Professor Minping Qian’s 70th birthday), Jiangfeng Feng, Wenjian Fu, Fengzhu Sun (editors), Springer

 

 USC Computational Biology Home Page

 

 

http://www-rcf.usc.edu/~fsun, fsun AT usc.edu, June 1, 2011